Medication Deprescribing in Psychiatry

Psychiatric medications can be life-changing, but there are times when reducing or simplifying a medication regimen becomes appropriate. Medication deprescribing is a structured, medically supervised process of carefully tapering or discontinuing medications when benefits, risks, and goals of care have changed. We provide a cautious, individualized approach to deprescribing that prioritizes safety, stability, and long-term mental health.

What Is Medication Deprescribing?

Deprescribing is the intentional, planned process of reducing or stopping medications that may no longer be needed, are causing side effects, or are no longer aligned with a patient’s goals. In psychiatry, this must always be done gradually and under medical supervision to avoid withdrawal effects, symptom recurrence, or destabilization.

Our Approach to Safe Deprescribing

We use a structured, patient-centered framework focused on stability and risk reduction.

When Deprescribing May Be Appropriate

Deprescribing may be considered when:

• Symptoms have been in sustained remission
• Side effects outweigh benefits
• Diagnosis is being re-evaluated
• Patient is clinically stable with strong supports
• There is a structured plan for monitoring

When Deprescribing Should Be Avoided or Delayed

Deprescribing may not be appropriate when:

• Recent psychiatric instability or relapse
• Active mood disorder symptoms
• High-risk conditions (e.g., uncontrolled bipolar disorder)
• Significant ongoing life stressors
• Lack of clinical follow-up or support